Abstract
Background
This study compared clinical and patient‐centered outcomes of subepithelial connective tissue graft (CTG) with and without enamel matrix derivative (EMD) in the treatment of multiple Class III‐IV Miller periodontal recession (REC) defects on mandibular anterior teeth.
Methods
This randomized clinical study evaluated 41 patients at 3 years follow‐up. One hundred and fifty‐six teeth were divided into two groups: test (CTG‐EMD, 79 teeth) and control (CTG only, 77 teeth). Clinical REC, keratinized tissue (KT) width, percentage of root coverage, patient‐centered outcomes were compared between the two groups.
Results
At 36 months follow‐up, patient level analysis showed that REC in the test group reduced significantly (5.71 ± 0.58 mm to 1.57 ± 0.85 mm) compared with the control group (5.94 ± 0.46 mm to 2.51 ± 0.62 mm) (P < 0.001), while KT width increased in the test group (1.51 ± 0.26 mm to 4.18 ± 0.34 mm) and was significantly greater than the control group (1.65 ± 0.21 mm to 2.90 ± 0.20 mm) (P < 0.001). At 36 months, tooth level analysis (Class III and Class IV groups) found less residual REC and increased KT in the test group compared with the control group (P < 0.01). Significantly less pain was reported at 2, 7, and 14 days follow‐up post‐surgery in the test group (P < 0.001).
Conclusions
The addition of EMD to CTG results in improved root coverage outcomes and higher amounts of KT width 36 months after treatment of Class III‐IV REC on mandibular anterior teeth. The adjunctive use of EMD also resulted in significantly reduced pain 14 days post‐surgery.
from
https://aap.onlinelibrary.wiley.com/doi/abs/10.1002/JPER.19-0058?af=R
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